N ω-nitro-L-arginine methyl ester inhibits inflammatory liver injury induced by interleukin-2
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منابع مشابه
Effect of inhaled NG-nitro-L-arginine methyl ester on Candida-induced acute lung injury.
STUDY OBJECTIVES Nitric oxide (NO) and peroxynitrite play a crucial role in acute lung injury (ALI). Whether NO synthase (NOS) inhibition is beneficial in the treatment of lung injury remains controversial. The objective of this study was to test the hypothesis that local inhibition of NOS in the lung reduces lung injury. DESIGN We developed a model of Candida-induced ALI in the mouse by IV i...
متن کاملN omega-nitro-L-arginine methyl ester reduces the incidence of IDDM in BB/E rats.
Evidence that nitric oxide (NO) is involved in cytokine-mediated islet beta-cell dysfunction and destruction in vitro has led to the hypothesis that increased production of NO may contribute to the pathogenesis of insulin-dependent diabetes mellitus (IDDM). This study demonstrates that oral administration of N omega-nitro-L-arginine methyl ester (an inhibitor of NO synthase) from 30 to 150 days...
متن کاملEpiscleral venous pressure responses to topical nitroprusside and N-Nitro-L-arginine methyl ester.
PURPOSE To determine the episcleral venous pressure (EVP) responses to nitroprusside (NP) and L-NAME. METHODS In anesthetized rabbits (n = 36), arterial pressure and IOP were measured by direct cannulation, and carotid blood flow and heart rate were measured with an ultrasound flowmeter and cardiotachometer. EVP was measured in two groups with a servonull system. Group 1 (n = 13) was given NP...
متن کاملN-nitro-L-arginine methyl ester influence on aluminium toxicity in the brain.
We investigated the influence of a non-specific nitric oxide synthase (NOS) inhibitor, N-nitro-L-arginine methyl ester (L-NAME), on brain nitrite concentration and acetylcholine esterase activity in AlCl3-treated Wistar rats. Animals were killed 10 min, three hours, three days and 30 days after the treatment and hippocampus and basal forebrain were removed. The biochemical changes observed in n...
متن کاملImprovement of Kidney Apelin and Apelin Receptor in Nitro-L-Arginine-Methyl Ester Induced Rats
1. Department of Sport Physiology, Faculty of Physical Education and Sport Sciences, University of Tarbiat Modarres, Tehran, Iran 2. Department of Sport Physiology, Faculty of Physical Education and Sport Sciences, University of Mazandaran, Babolsar, Iran 3. Cellular and Molecular Research Center, Research Institute for Endocrine Sciences, Shahid Beheshti University of Medical Sciences, Tehran,...
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ژورنال
عنوان ژورنال: Journal of Leukocyte Biology
سال: 1998
ISSN: 0741-5400
DOI: 10.1002/jlb.63.1.222